CAR-T Cell Manufacturing
Revolutionizing CAR-T Cell Manufacturing
Revolutionizing bioreactor manufacturing for life-saving CAR-T Cell therapies. Empowering faster, affordable, decentralized and streamlined production. We are utilizing a combination of ORGAN on CHIP and LAB on CHIP technology, AI, image recognition, multi-omics analysis and robotics to enhance the use and expansion in bioreactor process.
Talos: Revolutionizing T Cell Culture with Automated Systems
7Talos is at the forefront of advancing a cutting-edge automated cell culture system, designed to autonomously regulate and enhance T cell growth via sophisticated image analysis. This innovative system will seamlessly integrate the surveillance of T cells cultivated within microfluidic bioreactors, employing automated image acquisition and analysis.
The Power of AI in T Cell Culture
The core of this system lies in our state-of-the-art artificial intelligence (AI) technology.
It analyzes images in real-time, quantifying the area occupied by cells as a metric to gauge cell growth. Utilizing the insights derived from this analysis, a reinforcement-learning agent orchestrates the operation of the pumps, fine-tuning flow parameters dynamically. This results in a self-regulating feedback loop governed entirely by machine learning algorithms, which significantly enhances the efficiency of T-cell culture processes.
Microfluidic Technologies for Efficiency
A key advantage of this system is the incorporation of microfluidic technologies, which aim to streamline the process, making it more cost-effective and controlled. By reducing reagent usage and precisely managing the cellular environment, we can significantly decrease the operational costs. The synergy between machine learning and microfluidics enables the system to automatically and continuously adjust critical factors such as medium composition and renewal schedules in real-time. This adaptability is crucial for producing robust, customized autologous cell products suitable for individualized therapies.
Algorithmic Precision for T Cell Identification
The primary goal of our algorithm is to precisely identify T cells in a biological cell culture, providing essential data for monitoring their growth rate. Integrating a meticulously designed control mechanism, the system employs a syringe pump to dispense fluids in exact volumes, specifically adapted to the current stage of the cell culture. The secondary function of our algorithm involves a detailed analysis of T cell morphology, a critical aspect for identifying any deviations or anomalies in their growth patterns, thus ensuring the highest standards of quality and consistency in cell culture development.
Precision Efficiency in Cell Modification
Our approach combines the precision and adaptability of machine learning with the efficiency of microfluidic platforms. This integration not only enhances control and reduces time and errors associated with traditional methods but also minimizes reagent consumption. The result is a groundbreaking platform that dramatically improves the feasibility and viability of producing modified cells for CAR T treatments, reducing both production time and costs.
Live cell imaging
- Our solution streamlines CAR-T production, facilitates easy scalability, and ensures consistent processes, while simultaneously boosting efficiency, lowering expenses, and elevating the quality of the end product.
- 7Talos minimizes the risk of contamination.
- Our solution provides real-time monitoring and prompt identification of problems.
